Contamination on prepackaging exposes workers to risk when opening drug cartons or handling vials. True or False?

• A. True
• B. False
• C. Depends on packaging
• D. Not specified

Answer: (A)

Residues from hazardous drugs can linger on outer packaging before you ever access the drug inside, so opening cartons or handling vials can transfer contamination to gloves, skin, or surrounding surfaces. This means exposure can occur through dermal contact or by transferring contaminated material to other items or areas, even if the packaging is sealed. Because of this, the risk is real and ongoing during unpacking and handling of prepackaged drugs. To reduce it, follow strict hazardous-drug handling practices: wear appropriate PPE, perform hand hygiene before and after handling packaging, wipe down outer packaging with approved cleaners when protocol allows, and use containment methods or closed systems during unpacking and manipulation. This approach acknowledges that contamination risk exists at this stage and emphasizes measures to protect workers.