CVE stands for

• A. Containment Segregated Compounding Area
• B. Closed-System Transfer Device
• C. Air Changes Per Hour
• D. Containment ventilated exposure

Answer: (D)

A containment ventilated enclosure is a specialized, enclosed space designed to keep hazardous drug aerosols and powders from escaping into the surrounding area. It combines containment with active ventilation, typically achieving negative pressure and using HEPA filtration to remove contaminants before air is released. This setup protects workers and the environment during preparation, handling, and cleanup of hazardous drugs, and it aligns with safety standards like USP <800>.

That’s why the concept described by the option is the best fit: it emphasizes both containment and ventilation to minimize exposure. The other choices refer to different things—an area designation without the same enclosed containment, a device used during transfer rather than the workspace, or a ventilation rate metric—none of which capture the core idea of a dedicated, ventilated containment space.