Double gloves are to be worn during compounding hazardous drugs to provide an additional barrier of protection. True or False?

• A. True
• B. False
• C. Not necessary
• D. Only for infection control

Answer: (A)

Double gloves are recommended when compounding hazardous drugs to add an extra layer of protection against dermal exposure. Even high-quality chemotherapy gloves can allow trace drug permeation or suffer microtears during handling, splashes, or transfers. An inner pair remains as a backup if the outer glove becomes contaminated or torn, and removing the outer glove first helps protect the skin from exposure during glove changes. This layering is a standard part of PPE for hazardous drug handling and is emphasized in guidelines aiming to minimize dermal contact with cytotoxic or otherwise hazardous agents. Use gloves that are rated for chemotherapy, and replace gloves promptly if contamination is suspected or if a tear is noticed, following proper doffing procedures.