If a damaged HD contained is received, it should be sealed and transported to which device?

• A. Laminar flow hood
• B. C-PEC (BSC)
• C. PAPR isolation hood
• D. Standard chemical hood

Answer: (B)

Handling damaged hazardous drugs requires true containment to prevent exposure and environmental contamination. Seal the damaged container and transport it to a containment primary engineering control—the Class II biological safety cabinet. The C-PEC provides a physically enclosed workspace with negative pressure relative to the room and HEPA-filtered exhaust, capturing aerosols or splashes and preventing release into the surrounding area while you inspect or manage the material.

Other devices don’t offer the same level of containment. A laminar flow hood isn’t designed to contain hazardous drugs and can actually spread contaminants into the room. A PAPR hood is PPE for the wearer but does not enclose the hazard or provide the cabinet-level containment needed. A standard chemical hood handles chemical fumes but lacks the specific HD containment and HEPA filtration required, leaving exposure risk.