What is a containment primary engineering control (C-PEC) and its purpose?

• A. A positive-pressure cabinet that pushes air into the room
• B. A negative-pressure device used to contain aerosols and prevent exposure during HD handling
• C. A standard chemical fume hood
• D. A simple work surface

Answer: (B)

A containment primary engineering control is a ventilated enclosure used during hazardous drug handling to keep aerosols contained and protect the worker. It is kept under negative pressure relative to the surrounding room, so air flows into the enclosure rather than out, providing a barrier against any leaks. The exhaust from this device is filtered (usually with a HEPA filter) before release, capturing drug particles and preventing them from entering the room or reaching staff. This setup directly reduces exposure during preparation and handling of hazardous drugs.

A positive-pressure cabinet would push air into the room, increasing the chance of exposing others. A standard chemical fume hood is designed for general fumes but does not specifically meet the containment needs for hazardous drugs. A simple work surface offers no containment or airflow control at all.