What is the rationale for double gloving during HD handling?

• A. Outer layer provides splash protection and inner layer for continued protection if the outer layer becomes contaminated, with glove changes as required
• B. Double gloves are for fashion
• C. Outer layer provides splash protection and inner layer for continued protection if the outer layer becomes contaminated, with glove changes as required
• D. Double gloves are discouraged due to cost

Answer: (C)

Double gloving provides two protective barriers for hazardous drug handling. The outer glove acts as the first line of defense against splashes and direct contamination, while the inner glove serves as a continued barrier if the outer layer becomes contaminated or perforated. This setup allows you to continue working or to doffing safely by replacing the outer glove as needed without exposing the skin on the hand that’s still protected by the inner glove. Change gloves as required—after a task with potential contamination, when a glove shows a breach, or per your facility’s policy—to maintain protection. Safe doffing often involves removing the outer gloves first to minimize skin contact, then removing the inner gloves at the end, further reducing the risk of dermal exposure.