What is the role of closed-system transfer devices (CSTDs) in HD transfer?

• A. They eliminate the need for PPE
• B. They replace the need for proper hand hygiene
• C. They minimize leakage and aerosol generation during drug transfer
• D. They are optional for non-sterile areas

Answer: (C)

Closed-system transfer devices are designed to limit exposure to hazardous drugs by containing the transfer of drug solutions or powders, so leaks and aerosols are less likely to escape during preparation and administration. This engineering control helps protect you and the work environment from contamination. They do not replace PPE or proper hand hygiene—those protections are still essential components of safe HD handling. They are not optional in non-sterile areas where hazardous drugs are handled, but should be used as part of a comprehensive containment strategy. In short, their main role is to minimize leakage and aerosol generation during drug transfer.