Which description best defines a containment isolator?

• A. A Fume hood
• B. An enclosed glove box for contained HD handling
• C. A standard cabinet
• D. A cold room

Answer: (B)

A containment isolator is a sealed work enclosure that allows you to handle hazardous drugs without exposing yourself or the surrounding environment. It typically appears as an enclosed glove box with built-in gloves, so you manipulate the drugs from inside the containment area while the exterior remains protected. Negative pressure and HEPA filtration are common features to prevent any aerosols or particulates from escaping. This description fits best because it captures the essential elements: enclosure, built-in gloves for direct handling, and containment during HD work. Other options don’t provide the same level of enclosure and isolation: a fume hood protects through ventilation but is open to the room and doesn’t fully isolate the worker; a standard cabinet is merely for storage; a cold room is for temperature control, not containment of hazardous drugs.