Which device must be used when administering antineoplastic hazardous drugs?

• A. CSTDs
• B. Goggles
• C. Gloves
• D. Face shields

Answer: (A)

Handling antineoplastic hazardous drugs poses a real risk of skin contact, inhalation, and environmental contamination. A closed-system drug-transfer device is designed to keep the drug contained during every step of preparation and administration, preventing leaks, spills, and aerosol generation. That containment is what minimizes occupational exposure, making this device essential when working with these drugs. Other protective equipment like goggles, face shields, and gloves are important for splash protection and hand safety, but they do not provide the same level of containment as a closed-system transfer device and are used in addition to, not instead of, CSTDs. Therefore, the device that must be used is the closed-system transfer device.