Which device must be used when administering antineoplastic hazardous drugs?

• A. CSTDs
• B. Goggles
• C. Gloves
• D. Face shields

Answer: (A)

Maintaining a closed system during administration of antineoplastic hazards drugs is essential to protect staff from exposure. A closed-system transfer device is specifically designed to keep the drug contained as it’s drawn from a vial and transferred into an IV line or syringe, preventing leakage or aerosolization if connections shift or fail. This containment is what minimizes occupational exposure.

PPE like goggles, gloves, and face shields protect against splashes and direct contact, but they do not create or preserve a closed pathway for the drug. They alone cannot prevent environmental contamination or drug aerosols from escaping during transfer and administration. Therefore, the device that must be used is the closed-system transfer device.