Which of the following C-PECs would not be used as an alternative engineering control for a Class 2 BSC: CAI, CACI, Class 3 BSC, CAIC?

• A. CAIC
• B. CAI
• C. Class 3 BSC
• D. Class 1 BSC

Answer: (B)

The key idea is that an alternative engineering control must provide true containment and proper exhaust to protect the worker from hazardous drug aerosols. A Compounding Aseptic Isolator (CAI) enclosures the work, but it does not offer the same level of external containment and dedicated exhaust path required when substituting for a Class 2 BSC. In other words, CAI alone does not meet the containment and ventilation requirements set for alternatives to a Class 2 BSC, so it would not be used as an alternative. By contrast, containment-focused options like CACIs, Class III BSCs, and CAICs are designed to provide robust containment with appropriate exhaust/filtration and can be appropriate substitutes in the right setting.