Which pressure environment is not allowed for receiving HD?

• A. Negative
• B. Zero
• C. Neutral
• D. Positive

Answer: (D)

The main idea is containment through airflow direction. When hazardous drugs are received, the area should be under negative pressure so that air flows into the room rather than out to adjoining spaces. This inward airflow helps prevent any drug vapors or contamination from escaping into hallways or other areas, protecting staff and other personnel.

A positive pressure environment would push air from the receiving room into surrounding areas, carrying any HD residues with it. That increases exposure risk outside the room, which is exactly what we want to avoid. Neutral (zero) or no pressure difference doesn't provide containment either; door openings can allow contaminants to drift into adjacent spaces, especially if there are leaks or disturbances.

Thus, receiving hazardous drugs in a positive pressure environment is not allowed because it compromises containment and increases exposure risk.