Which procedure documents the effectiveness of cleaning in hazardous drug environments?

• A. Cleaning
• B. Air monitoring
• C. Water testing
• D. Surface wipe sampling

Answer: (D)

In hazardous drug environments, proving that cleaning actually removes residues requires objective evidence from surface testing. Surface wipe sampling does this by wiping predefined surfaces and analyzing the wipes for residual hazardous drug. The results show whether surface contamination is below established acceptance criteria, providing direct documentation that cleaning procedures are effective.

Air monitoring, while useful for assessing airborne contaminants and containment effectiveness, does not demonstrate how clean surfaces are. Water testing isn’t used to verify surface cleanliness, and simply performing cleaning isn’t enough without measurement to prove its effectiveness.