Wipe sampling interval?

• A. Performed annually
• B. Performed every 2 years
• C. Performed at least every 6 months for HD residue
• D. Performed monthly

Answer: (C)

Wipe sampling interval is about how often you check surfaces for hazardous-drug contamination to verify that cleaning and containment controls are working. The recommended cadence is at least every six months for HD residue. This semiannual interval provides regular surveillance to catch any increasing contamination without being overly burdensome in terms of time and resources. Sampling more often, like monthly, isn’t typically necessary for routine surveillance and can strain resources, while waiting only a year or more could let issues go undetected. If a surface previously tested above the action level, or if processes or areas change, you would increase the frequency until results remain below the threshold. Baseline and trend data help ensure ongoing safety in areas where hazardous drugs are prepared or handled.